The High Flow Rate (HFR) Cell Disruptor is the premier production model in the Constant Systems lineup, designed to offer unparalleled lysis efficiency consistent with the standard CSL systems across a full range of processing pressures. The HFR delivers significantly higher flow rates than competitor products, reaching up to 150 L/hr. This capability enables rapid processing of the entire contents of production-scale fermenters or bioreactors, efficiently handling even challenging cell types without the need for prior pelleting and re-suspending.
Specifications
- Unique Disruption Mechanism: Incorporates Constant Systems’ unique disruption mechanism and precise hydraulic control system for optimal performance.
- Digital Pressure Control: Disruption pressure is digitally set and displayed, offering a standard range of up to 40Kpsi.
- High Flow Rate: Capable of processing up to 150 L/hr at maximum pressure, making it ideal for large-scale production needs.
- Automatic Shutdown: Features an automatic shutdown mechanism for when the process is complete, enhancing safety and convenience.
- Stable Pressure: Maintains consistent and stable pressure throughout the disruption cycle, ensuring uniform sample processing.
- Versatile Configurations: Offers various configurations for inlet and outlet connections, facilitating direct integration with upstream and downstream equipment.
- Comparable Performance: Delivers performance on par with the existing range of Constant Systems Ltd cell disruptors.
- Material Quality: Contact materials include 316L and F51 duplex stainless steel or equivalent, EPDM, ensuring durability and compatibility with a wide range of samples.
- Compliance and Validation: IQ/OQ documentation available upon request for compliance and validation processes.
Machine Specifications
- Dimensions: 1650 x 900 x 1250 mm (LxWxH)
- Weight: 875 kg
- Accumulator Dimensions: 650 x 1700 mm
- Accumulator Weight: 210 kg
The High Flow Rate Cell Disruptor is engineered for those in need of high-efficiency, large-volume cell disruption capabilities, without compromising on lysis efficiency. With its advanced features and robust design, the HFR is ideally suited for large-scale biotechnological and pharmaceutical applications, ensuring rapid processing with exceptional control and reliability.
“we were adamant we should only have Constant Systems cell disruptors in our new building” – The Rosalind Franklin Institute