The Continuous Flow Cell Disruptor

The Continuous Flow (CF) Cell Disruptor is available in two models, the CF1 and CF2. Both benefit from Human-Machine Interface (HMI) for control, boast a maximum process pressure of 40kpsi (2700 bar), and feature integrated sample cooling jackets, a 200mL inlet reservoir (hopper), and an auto shut-down function upon process completion.

Both models are suitable for processing fluid or re-suspended sample types.


  • User-Friendly: Simple, quick, and straightforward to use, requiring only a standard electrical supply, with no need for compressed air or bottled gas.
  • Efficient Start-Up: No priming or purging needed before use; any air in the system is processed without negatively affecting the sample or the equipment.
  • Safety Features: Includes a stainless steel tray to catch any accidental spillages.
  • Precision Control: Disruption pressure is digitally displayed and can be easily and accurately set between 1-40 kpsi.
  • Versatile Processing Capability: Suitable for fluid, re-suspended, viscous, tissue, plant, and frozen sample types.
  • Temperature Management: Collection cups can be transferred to and from ice or a freezer to maintain sample temperature.
  • Consistent Performance: Constant Systems’ hydraulic control ensures consistency in every process, with 99% of the sample processed at the set pressure.
  • Ease of Cleaning: Offers process flow cleaning and manual cleaning options, compatible with standard cleaning media.
  • High-Quality Materials: Product path materials include industry-standard Stainless Steel 316L and F51 duplex, EPDM, GLFPTFE, and PEEK 450G.

CF1 Specifications

  • Dimensions: 605x700x740 mm (DxWxH)
  • Weight: 130 kg
  • Electrical Supply: Standard single-phase, with three-phase required in some areas of the Americas.

CF2 Specifications

  • Dimensions: 720x700x1340 mm (DxWxH)
  • Weight: 240 kg
  • Electrical Supply: Standard three-phase electricity.


Who to contact

Emma Craughan
Technical Sales Specialist

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    The Continuous Flow Cell Disruptor from Constant Systems exemplifies the pinnacle of efficiency and adaptability in cell disruption technology. Depended upon in academic research, biotechnology, and pharmaceutical manufacturing, the CF series offers scalable, reliable solutions for continuous flow processing, ensuring high-quality results with unparalleled precision.

    Constant Systems. Cell disruption at a constant pressure giving 99% cell disruption with one pass.