SYNENTEC NyONE Compact Cell Imager

SYNENTEC’s compact automated cell imager – the NYONE – is the ideal solution for harnessing the advanced imaging technology of the CELLAVISTA while saving valuable bench space. Ideal for medium throughput labs, the NYONE fully automated, is compatible with a wide range of SBS format plate types, and is easy to install in any lab. Data analysis is via SYNENTEC’s inbuilt powerful image processing tools which gather robust data and are simple to use with a variety of configurable data export options.

Applications include:

  • Single Cell Cloning (SCC)
  • Fluorescence Activated SCC (FASCC)
  • Confluence monitoring
  • Transfection Efficiency
  • Cell Counting/viability
  • Antibody Quantification & glycan analysis – PAIA
  • Cell Apoptosis Monitoring
  • Virus Quantification
  • iPS Cell Monitoring
  • Viral Transduction
  • Toxicity Studies
  • Wound Healing assays

Feature advantages of the NYONE:

  • Agitation-free imaging of adherent and suspension cells through harmonic motion
  • Complete scan of 96-well microplate in ~5 minutes
  • Excellent well edge illumination of microplates
  • Seamless image stitching
  • Available in brightfield and with 4 fluorescence excitation sources with up to 5 fluorescence emission filters
  • Up to 3 different magnifications
  • Reliably reproducible measurements through high-precision scan stage control

There are two variations of the NYONE:


Featuring high-sensitivity 16-bit sCMOS cameras combined with high numerical aperture objectives, the SCIENTIFIC instrument series achieve better resolution in a higher contrast and allow for better detection of weak fluorescent signals. Specifically designed for cancer research and drug discovery applications, the NYONE SCIENTIFIC achieves remarkable high content imaging in medium throughput.

4K Line

Native 4K imaging does not compromise throughput, it simply increases resolution and clarity. The NYONE has a wide range of sophisticated applications, and is ideal for confirming monoclonality in SCC applications without missing a single cell fragment – all in one compact instrument.

Ellen’s take on this product


Ellen Harrington
Technical Sales Specialist

Versatile: Time saved by automation combined with precision optics and a wide range of applications make these imagers an integral part of any CLD workflow. Both extremely robust, the Cellavista offers higher throughput and is perfect for automated environments, while the smaller NyONE is ideal for medium-throughput laboratories with limited bench space. An extensive range of applications within Cell Line Development, Vaccine Research, Drug Discovery, Cancer Research, Stem Cell Studies and others makes these imagers the ultimate cell culture instrument.

Innovative: SYNENTEC are constantly developing new applications to meet the needs of customers. Technical assistance provided by the SYNENTEC team as well as local applications training means the user is supported from day 1.

Did you know?

For customers working in cGMP environments, SYNENTEC have developed YT AUDIT, a validation software which meets requirements for CFR21 part 11 compliance.

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    More on SYNENTEC

    SYNENTEC’s team of engineers, software developers and biologists have combined their knowledge to develop automated, high throughput cell culture microscopes and fast, easy to use image analysis software. They continuously develop and perfect the imaging systems and work with customers to create bespoke applications to meet their individual cell imaging and analysis needs.

    SYNENTEC provide the most versatile cell imagers on the market.