Solaris M-Series 30-200L – SIP Fermenters & Bioreactors

Designed for microbial fermentation and cell cultivation

The Solaris M-series includes standard SIP fermenters/bioreactors available in a range of six different volumes from 30 up to 200 litres, with a wide range of options and accessories.

The Solaris M-Series: Standard SIP Pilot-Industrial Solutions

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Matt’s take on this product

Matt Wright
Technical Sales Specialist

Introducing the Solaris M-Series: Your Next Step to Industrial-Scale Success. As an essential intermediate step in the scaling-up process, the M-Series Standard SIP Pilot-Industrial Solutions offer an extensive range of six different volumes, ranging from 30L up to 200L, along with a plethora of options and accessories. With the M-Series, you can experiment with re-sterilisable addition systems, gravimetric flow control, SIP sampling, harvest valves, and much more. Designed for those transitioning from small-scale R&D to full product scale, the M-Series offers a perfect testing ground for your processes at the pilot scale. Elevate your experimentation and take a leap towards industrial-scale success with the Solaris M-Series.

Specialist: Solaris not only offers off-the-shelf systems, but turnkey solutions for their customers. They can assist their clients in the design and manufacturing of completely integrated turn-key process plants for nearly any application, whether that be biopharma, biotech, food and beverage, and many more. .

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    Features & Benefits

    • 6 different volumes: 30 L, 50 L, 75 L, 100 L, 150 L, 200 L.
      3:1 H/D ratio.
    • Parts in contact with the culture AISI 316 L, other parts AISI 304.
    • Finishing: mirror polished (internal and external).
    • Compact design.
    • Double jacket (side/bottom), for higher heat transfer efficiency and optimal temperature control.
    • Bacteria (Toro sparger, Rushton impellers) and cell cultures (Sintered sparger, Marine impellers) configurations available.
    • Welded baffles.
    • Wide range of measurement and control options for cell cultures and aerobic/anaerobic microbial fermentations, including temperature, pH, dO​2​, dCO​2​, redox, antifoam, level, conductivity, weight, cell density (total cells, viable cells).
    • Modbus digital sensors.
    • Suitable for batch, fed-batch and continuous processes.
    • Stainless-steel industrial PCS ​LEM_2​, with a selectable number of peristaltic pumps, choosing between Watson Marlow WM 114, WM 313 and WM 520.
    • Powerful and accurate (1 RPM) brushless motor, mounted on top.
    • Different gas mixing strategies with a selectable number of TMFCs or solenoid valves, for air, O​2​, CO​2​ and N​2​.
    • SALAS (Solaris Sterile Liquid Addition System) included in the standard configuration.
    • Up to 2 steam bridges (re-sterilizable diaphragm valves for inoculum/feedings) can be added in option (with manual or automatic sterilization control).
    • Non-SIP sampling and harvest valves are included in the standard configuration. Steam SIP lines can be added in option. Manual or automatic sterilization.
    • TK connection.
    • Tri-Clamp stainless steel piping.
    • Single mechanical seal. Double mechanical seal, with automatic lubrication though steam condensate loop available in option.
    • Thermoregulation loop consisting of n.2 heat exchangers and recirculating pump.
    • Separate drains: cooling water return, condense drain to waste, hot condense return.
      Gravimetric flow control (option): feed rates controlled through weight measurement.
      CIP system options: n. of removable spray balls or integrated system (recirculating pump + n. of removable spray balls + software automation). N. of spray balls depending on vessel volume.
    • Optional vessel empty sterilization.

    Automation and Software

    Innovative SCADA software​ ​LEONARDO​ ​3.0​: a smart and user-friendly controller designed to provide a high level of automated management of the fermentation/cultivation processes.

    • 24” coloured touch screen industrial HMI.
    • Included in the equipment supply.
    • Data extraction in .csv format.
    • Remote access via PC, tablet or smartphone, with QR code scanning or dedicated portal.
    • Remote control for after sale assistance.

    Solaris is a modern, dynamic company specialising in the production of high quality and innovative fermenters and bioreactors for the biotechnology industry. 

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