Vaccine Research

High throughput development of new vaccines represents only a small part of what can be achieved in the field of virus research with SYNENTEC’s automated cell imagers. Amplify your work with SYNENTEC’s wide range of imaging applications and reduce time to market.

SYNENTEC’s extensive experience in the field of virus research and vaccine development enables us to provide a wide range of applications in this area for our customers.

The high-throughput imaging systems CELLAVISTA® and NYONE® accelerate your work in various areas of virological research with their high-resolution imaging in brightfield and diverse fluorescence channels.

SYNENTEC support the vaccine research and development (Influenca, Noro, SARS-CoV-2, Malaria, HIV etc) for human and veterinary vaccines as well as the CLD upstream processes for production purposes.

Viral titre quantification & infectivity determination

    • Label-free plaque assay
    • Endpoint dilution assays (TCID50)
    • Plaque reduction neutralization test (PRNT) (Virus neutralization assay)
    • Focus forming assay (FFA)
    • Immunofluorescence foci assays (IFA)
    • Measurement of host cell viability & viral cytopathic efects (Cell confluence, Live/Dead, Apoptosis…)
    • Viral Pathogenesis (morphological change in infected host cells)

Vaccine technology

  • in vitro immune responses to vaccines
  • Vaccine vector testing in transduction efficiency
  • Immunologic in vitro studies
  • Reverse vaccinology (ELISpot and FluoroSpot)

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