Single use scale-down centrifuge for process development and small batch manufacturing
The Pneumatic Scale Angelus’ CARR Centritech UFMini® is the scaled-down version of our successful UniFuge® single-use centrifuge, designed for harvesting CHO, Stem, and other cells for biotech and pharmaceutical applications. This user-friendly system is intended for use in cleanrooms, in laminar fl ow hoods, and on benchtops.
- Processes scalable to Unifuge Pilot and U2k
- Flow rate from 29-1000 ml/min
- Variable g-force up to 3000 x g
- Continuous discharge of supernatant and intermittent discharge of cell culture
- Lightweight single-use module with tube set
- Optional data acquisition for SCADA System via Ethernet connection
- Low noise level (below 80 dB) during operation
The UFMini separation system utilises a gamma irradiated, single-use module that requires NO CIP and NO SIP.
The single-use module is supplied with a tubeset, which can be readily tube welded to your single-use bioreactor connections (customer-specified single-use connectors available upon request).
The UFMini is completely automated with flexible cycle parameters. The feed suspension is gently pumped to the separation zone of the single use module and the cells centrifugally settle to the outer radius, while the clarified supernatant is continuously discharged. Once the user programmed cycle timer has expired, the controller stops the rotor and discharges the cells. This cycle automatically repeats for a user selectable number of cycles based upon bioreactor volume.
Pneumatic Scale Angelus (Carr Centritech)
PSA’s CARR Centritech division is a global leader in the design and manufacture of liquid/solid centrifugal separation systems. Their range of continuous flow centrifuges offers the ability for true scale up of contained processes, from development to production for microbial, yeast, animal cell and fine chemical applications. All centrifuge systems are developed in a state of the art manufacturing facility in Clearwater, Florida. BioProcess Engineering Services Ltd. have worked with Carr Centritech in the UK since 1997.