HPNE ClearMixx Single-Use Mixing System

A new and innovative single-use mixing system that utilises a low-sheer Quattroflow pump, allowing the user to create a uniform, completely homogenous mixture.

The ClearMixx single-use mixing system has an inlet and outlet port which are both connected to a Quattroflow pump. Through the outlet port, the media is be pumped out of the bag, circulated through the pump (and other possible post-mixing processes), and is then pumped back into the bag through a machined flow path with a smooth fluid stream.

Features & Benefits

  • Performs liquid/liquid and powder/liquid mixing
  • Dispersion plate designed to efficiently mix the most challenging buffer, media, and biopharmaceutical ingredients
  • No shaft, seals, or bearings inside the single-use mixer system, allowing for low mechanical shear
  • Cuboid shape improves mixing efficiency and is scalable from 50L to 500L
  • Flexible working range from 20% of nominal bag size
  • Mixer base is tapered to allow complete draining of fluid
  • Capable of local or remote operation via the touchscreen PLC
  • Sight glasses on three sides enable the user to visually control the mixing process
  • Simultaneously mix and run a unit of operation
  • Unique cube shaped bag
  • Open architecture
  • Produces a completely homogenous mixture
  • Available in stainless steel
  • Available in custom sizes

More on HPNE

Eliminate your bioprocessing challenges with HPNE comprehensive selection of products. With over 100 combined years of industry experience, HPNE cover a wide range of disciplines, backgrounds, and expertise, including engineers, biologists, scientists and product managers. Your research, development, and manufacturing process is unique – the solutions to advance it should be too.

Sean’s take on this product

Sean Doran
Technical Sales Specialist

Flexible: With HPNE custom assemblies, you can have exactly what you need, to your precise requirements, regardless of component brand, company or part. Available in single quantities, HPNE provide effective solutions with no commitment requires for larger quantities.

Interested: Ensuring you have the correct solution for your process, HPNE’s experts support you from conception to delivery.

Did you know?

HPNE have short lead times, ahead of the game among their competitors.

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    Customisable features

    • Integrated load cells on custom carts
    • Integration of any sensor that provides, 4-20mA, RE-232
    • Built-in level sensors and conductivity sensors

    In combination with a feed pump, the ClearMixx system becomes a multi-purpose system for

    • Mixing solutions by recirculation without rotating wetted parts in the bag
    • Post-mixing processes like sterile filtration, TFF and chromatography can be run simultaneously
    • Optional integration of in-line sensors (flow, pH, conductivity, temperature, UV) and level sensors
    • Optional auto dosing pump based on conductivity set point


    High Purity New England (HPNE) supplies and manufactures single-use assembly products, connectors, tubing and components.