The Integrity™ PadReactor™ system is perfectly suited to laboratory environments, process development centres, clinical material supply and flexible GMP manufacturing.
The PadReactor offers an open architecture controller platform, which gives the end user the opportunity to choose a preferred controller or use an existing control system.
The bioreactor vessel, which offers comparable functionality to classical stirred tank bioreactors, is a single-use bag integrating an internal paddle mixing and sparger system. This innovative bag design allows a non-invasive connection to the system. The paddle is enclosed in a medical grade ULDPE sleeve, made from the same contact material as the bag itself, and is coupled on top of the vessel with the mechanical mixing head.
As with all ATMI LifeSciences' single-use systems, the Integrity PadReactor utilises disposable mixing bags made from Integrity TK8 bioprocess film. The product-contacting layer of TK8 film is blow-extruded in-house by ATMI under cleanroom conditions using medical-grade ultra low-density polyethylene resin. It is then laminated to create a gas barrier film of exceptional cleanliness, strength, and clarity that is animal derived component free (ADCF) and complies fully with USP Class VI requirements.
The Integrity PadReactor single-use bioreactor consists of the following:
- Drive Unit
- Mobile Retaining Tank
- Bioreactor Vessel
Benefits
Superior mixing capabilities with highly reduced shear stress
Innovative sparging device with better oxygenation and kLa
Adapted for cultivation of suspended or adherent cells at very high densities
Compatible with most cell culture processes
Scalable customisable system
No need for CIP/SIP (disposable bag technology)
Avoids cross contamination risks
Very low working volume
For more information please contact us on 01795 411531 or visit www.atmi-lifesciences.com
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